Glyburide for Type 2 Diabetes will make you fat

So I started back on glyburide once a day in the mornings. My sugars are definitely doing better now, but I have started to gain weight. Not sure what all is causing this.

I find myself stressing about getting a sugar low so I try and eat things more regularly. I definitely eat more carbs since I am worried that not enough is going to bring about a low.

I am eating more junk, especially sugary stuff. Part of it is my relaxation on the diet since I am eating more medication, but part of it seems to be an incredible urge to do so that does not seem to be in my control. I used to have urges before but I could get control on them in a day or two. This time it is over 2 weeks and still not slow down. Not sure if this is glyburide doing something internally, or my brain, or a combination.

Net effect of taking the medication, I am feeling a little more balanced through the day as my sugars are controlled, but the weighing balance is tending to move into the higher range.

Sigh, just another thing we diabetics have to balance in life.


Anonymous said…
I started on Glyburide in late October. Since then, I have lost maybe 16 pounds, which is an extraordinary amount of weight for me. Before going on the Glyburide, I was on Metformin 850/twice a day. (I was losing weight very slowly on Metformin.) I have hypoglycemic episodes several times a week, usually three or four hours after breakfast. Sometimes snacks don't help. I have increased my carb intake a little bit, but I really haven't changed my diet much, which is probably why I hypo all the time! Some people think that more insulin production results in weight gain (a lot of Type 1s can attest to that since they inject insulin), but sometimes I wonder if overcompensating with food for hypos is why the weight gain occurs in part. In your case, it might be. Clearly, Glyburide is too strong for you and me. We might need to go off it or get a dosage reduction.

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